Drug Absorption

Factors Affecting Drug Absorption

Drug affecting the gastric emptying rate and drug absorption.

In a previous paper (1) we reported that administration of sucrose markedly decreased the rate of gastric emptying and of intestinal absorption of aminopyrine in intact rats.

Integro-differential models for percutaneous drug absorption

In this paper we propose a new mathematical models for percutaneous absorption of a drug based on integro-differential equations. We study the qualitative properties of the solution of the models and its numerical approximation. Simulation of proposed numerical methods is carried out.

Absorption enhancing excipients in systemic nasal drug

Intranasal drug delivery is becoming an increasingly important form of drug administration for chronic and chronic-intermittent diseases. Important new applications currently in development include drugs for diabetes, osteoporosis, obesity, certain types of convulsive disorders, migraine headaches, symptomatic pain relief, nausea, and anxiety, among others. Transmucosal absorption across the na...

Gastric emptying and drug absorption before surgery.

The rate of paracetamol absorption following oral administration has been used as a model of drug absorption and as an indirect estimate of the rate of gastric emptying before and after elective or emergency surgery in 13 adult patients. The rates of paracetamol absorption before and after surgery were not significantly different and compared well with results obtained previously in normal volu...